0660 Higher Amounts of REM Sleep without Atonia Predict Phenoconversion To Defined Neurodegenerative Disorders in Idiopathic REM Sleep Behavior Disorder
نویسندگان
چکیده
منابع مشابه
REM sleep behavior disorder and REM sleep without atonia in patients with progressive supranuclear palsy.
STUDY OBJECTIVE To compare sleep characteristics, rapid eye movement (REM) sleep without atonia, and REM sleep behavior disorder (RBD) in patients with progressive supranuclear palsy (tauopathy), patients with Parkinson's disease (a synucleinopathy), and control subjects. DESIGN Sleep interview, overnight polysomnography, and Multiple Sleep Latency Tests. PATIENTS Forty-five age- and sex-ma...
متن کاملSeverity of REM atonia loss in idiopathic REM sleep behavior disorder predicts Parkinson disease.
BACKGROUND Over 50% of persons with idiopathic REM sleep behavior disorder (RBD) will develop Parkinson disease (PD) or dementia. At present, there is no way to predict who will develop disease. Since polysomnography is performed in all patients with idiopathic RBD at diagnosis, there is an opportunity to analyze if baseline sleep variables predict eventual neurodegenerative disease. METHODS ...
متن کاملREM sleep behavior disorder (RBD)
Background. REM sleep behavior disorder (RBD) is parasomnia characterized by dream enactment and enabled by disruption of physiologicalmuscle atonia during REM sleep. Over the past few years, diagnostic criteria and the methods used to confirm diagnosis have been updated. Objective. In this review article, the current knowledge regarding RBD diagnosis and treatment is presented. Methods. A sele...
متن کاملNeurodegenerative Disorder Risk in Idiopathic REM Sleep Behavior Disorder: Study in 174 Patients
OBJECTIVE To estimate the risk for developing a defined neurodegenerative syndrome in a large cohort of idiopathic REM sleep behavior disorder (IRBD) patients with long follow-up. METHODS Using the Kaplan-Meier method, we estimated the disease-free survival rate from defined neurodegenerative syndromes in all the consecutive IRBD patients diagnosed and followed-up in our tertiary referal slee...
متن کاملSleepiness in Idiopathic REM Sleep Behavior Disorder and Parkinson Disease.
OBJECTIVE To determine whether patients with idiopathic and symptomatic RBD were sleepier than controls, and if sleepiness in idiopathic RBD predicted earlier conversion to Parkinson disease. METHODS The Epworth Sleepiness Scale (ESS) and its determinants were compared at the time of a video-polysomnography for an RBD diagnosis in patients with idiopathic RBD, in patients with Parkinson disea...
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ژورنال
عنوان ژورنال: Sleep
سال: 2018
ISSN: 0161-8105,1550-9109
DOI: 10.1093/sleep/zsy061.659